Malawi

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HIV/AIDS Statistics for Malawi

Total population in thousands (2007): 13,925*
Number of people living with HIV (2007): 930,000*
Adults aged 15 to 49 prevalence rate (2007): 11.9*
Adults aged 15 and up living with HIV (2007): 840,000*
Women aged 15 and up living with HIV (2007): 490,000*
Children aged 0 to 14 living with HIV (2007): 91,000*
Deaths due to AIDS (2007): 68,000*
Orphans due to AIDS aged 0 to 17 (2007): 560,000*
Estimated antiretroviral therapy coverage (Dec 2007): 35%†
Population aged > or = to 15 years who received an HIV test (2007): 660,000†
Number of tests per 1000 population aged ≥ to 15 (2007): 89†
Estimated number of pregnant women living with HIV (2007): 73,000†


Ongoing biomedical HIV prevention research trials in Malawi
Microbicides Partner Treatment

Microbicides

Trial: Safety and acceptability of dapivirine gel, conducted using daily monitored adherence in healthy HIV-negative women [IPM 014A]
Phase: I/II
Product Being Tested: Dapivirine gel
Sponsor, funder, developer, collaborator: International Partnership for Microbicides, Johns Hopkins Project, College of Medicine
Total participants: 320
Countries: Kenya, Malawi, Rwanda, South Africa
Trial sites in Malawi:Blantyre
Results expected: n/a
For more information: http://clinicaltrials.gov/ct2/show/NCT00917904?term=IPM014B&rank=1
Trial: Dapivirine vaginal ring safety [IPM 015]
Phase: I/II
Product Being Tested: Dapivirine vaginal ring
Sponsor, funder, developer, collaborator: International Partnership for Microbicides
Total participants: 280
Countries: South Africa, Kenya, Malawi, Rwanda, Tanzania
Results expected: n/a
For more information: http://www.clinicaltrials.gov/ct2/show/NCT01071174?term=dapivirine+vaginal+ring&rank=1

Trial: VOICE (MTN 003)
Phase: IIb, safety and effectiveness
Product being tested: Tenofovir gel; oral TDF; oral TDF/FTC
Sponsor, funder, developer, collaborator: CONRAD, DAIDS/NIAID, Gilead, MTN, NICHD, NIMH
Total participants: 5,000 heterosexual women
Countries: Malawi, South Africa, Uganda, Zimbabwe
Results expected: Ongoing/2013

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Partner Treatment


Trial: Evaluation of the effectiveness of two antiretroviral treatment strategies to prevent HIV transmission in HIV-serodiscordant couples [HPTN 052]
Phase: III
Product Being Tested: Highly active antiretroviral therapy for HIV prevention
Sponsor, funder, developer, collaborator:HIV Prevention Trials Network, Malawi College of Medicine-Johns Hopkins University, University of North Carolina Lilongwe
Total participants: 1,750 couples
Countries: Botswana, Brazil, India, Kenya, Malawi, South Africa, Thailand, Zimbabwe
Trial sites in Malawi: Blantyre, Lilongwe
Results expected:
For more information: http://www.hptn.org/research_studies/hptn052.asp
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*WHO, UNAIDS, and UNICEF. Epidemiological Fact Sheet on HIV and AIDS: Core data on epidemiological and response Malawi 2008 Update. 2008. http://www.who.int/globalatlas/predefinedReports/EFS2008/full/EFS2008_MW.pdf
† WHO, UNAIDS, and UNICEF. Towards universal access: scaling up priority HIV/AIDS interventions in the health sector: Progress Report. 2008. http://www.who.int/hiv/pub/towards_universal_access_report_2008.pdf