Thailand

HIV/AIDS Statistics for Thailand

Total population in thousands (2007): 63,884*
Number of people living with HIV (2007): 610,000*
Adult aged 15 to 49 prevalence rate (2007): 1.4*
Women aged 15 to 49 prevalence rate (2007): 1.2*
Adults aged 15 and up living with HIV (2007): 600,000*
Children 0 -14 living with HIV (2007): 14,000*
Women aged 15 and up living with HIV (2007): 250,000*
Deaths due to AIDS (2007): 30,000*
Estimated antiretroviral therapy coverage (Dec 2007): 61%


Ongoing biomedical HIV prevention research trials in Thailand

Vaccines

Trial: Trial to evaluate the safety and immunogenicity of a candidate prophylactic DNA prime-rFPV boost HIV vaccination strategy; the HIV Netherlands Australia Thailand Research Collaboration vaccine [NCHECR-AE1]
Phase: I/IIa
Product Being Tested: A candidate prophylactic DNA prime-rFPV boost HIV vaccination strategy (rFPV-HIV-AE;pHIS-HIV-AE)
Sponsor, funder, developer, collaborator: National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Thai Red Cross AIDS Research Centre
Total participants: 8
Countries: Thailand
Trial sites in Thailand: Bangkok
Results expected: n/a

Trial: RV262
Phase: I
Start Date: September 2010
Sponsor, funder, developer: NIAID
Total participants: 92
Vaccine(s): Prime: PENNVAX-G DNA (ENV & GAG) Administered by Intramuscular Biojector 2000 or CELLECTRA Intramuscular Electroporation Device Boost: MVA-CMDR (HIV-1 CM235 ENV/CM240 GAG/POL)
Clade: A, B, C, D, E

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Pre-Exposure Prophylaxis

Trial: Pre-Exposure Prophylaxis Initiative [iPrEx]
Phase: III
Product Being Tested: Daily oral TDF/FTC (Truvada®)
Sponsor, funder, developer, collaborator: National Institute of Health, Bill and Melinda Gates Foundation, Fenway Community Health, San Francisco Department of Public Health
Total participants: 2,499
Countries: Brazil, Ecuador, Peru, South Africa, Thailand, US
Trial sites in US: Boston, MA
Results expected: Announced in Q4 2010. For more information visit theGlobal iPrEx page or AVAC's iPrEx page


Trial: Bangkok Tenofovir Study [CDC 4370]
Phase: II/III
Product Being Tested: Daily oral TDF
Sponsor, funder, developer, collaborator: US Centers for Disease Control and Prevention
Total participants: 2,400
Countries: Thailand
Trial sites in Thailand: Bangkok
Results expected: Q4 2010
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Partner Treatment

Trial: Evaluation of the effectiveness of two antiretroviral treatment strategies to prevent HIV transmission in HIV-serodiscordant couples [HPTN 052]
Phase: III
Product Being Tested: Highly active antiretroviral therapy for HIV prevention
Sponsor, funder, developer, collaborator: HIV Prevention Trials Network, Chiang Mai Univeristy AIDS Prevention; Chiang Mai University, Maharaj Nakorn Chiang Mai Hospital, Family Health Clinic;
Total participants: 1,750 couples
Countries: Botswana, Brazil, India, Kenya, Malawi, South Africa, Thailand, Zimbabwe
Trial sites in Thailand: Chiang Mai
Results expected: n/a
For more information: http://www.hptn.org/research_studies/hptn052.asp
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*WHO, UNAIDS, and UNICEF. Epidemiological Fact Sheet on HIV and AIDS: Core data on epidemiological and response Thailand 2008 Update. 2008. http://www.who.int/globalatlas/predefinedReports/EFS2008/full/EFS2008_TH.pdf
†WHO, UNAIDS, and UNICEF. Towards universal access: scaling up priority HIV/AIDS interventions in the health sector: Progress Report. 2008.
For more information: http://www.who.int/hiv/pub/towards_universal_access_report_2008.pdf