Today there are several trials evaluating the use of ARV-based prevention in people with HIV. The goal of these "treatment as prevention" strategies is to reduce viral load and thereby reduce individuals’ infectiousness. Data gathered from serodiscordant couples enrolled in a trial of HSV-2 treatment for HIV prevention showed that effective ARV treatment reduced HIV transmission by approximately 92 percent. These data were not from a randomized controlled trial and ongoing trials—many listed below—will provide additional information. Not included in this table are the many ecological studies of ART impact on HIV prevalence in different settings.

A PDF version of the following chart is also available.