Vaccine Resources
Vaccine
Trial Table (PDF) - AVAC, March 2010
Table contains information about ongoing trials of HIV vaccine trials.
Vaccine Fact Sheet (PDF) - AVAC
This fact sheet provides basic information on AIDS vaccines, one of the options being tested now as part of the effort to identify additional tools to reduce the risk of HIV transmission. There are no vaccines as yet to prevent HIV infection.
Thai AIDS Vaccine Trial Update page - AVAC
This webpage provides materials to help our readers in anticipating and understanding the results of the Phase III AIDS vaccine trial in Thailand.
Vax update page: Step, Phambili, PAVE 100, and HVTN 505 - AVAC
This page includes information on the Step and Phambili trials of Merck's MRK-Ad5 vaccine candidate (immunizations were stopped in September 2007) as well as information on the NIH Vaccine Research Center's DNA prime/Ad5 boost vaccine strategy, initially planned to be tested in the proposed PAVE 100 vaccine trial. The strategy is now slated to be tested in a test-of-concept trial known as HVTN 505.
Estimating the Impact of an AIDS Vaccine in Developing Countries, IAVI Policy Brief - IAVI, 2009
This policy brief examines the potential impact that an AIDS vaccine could have on the pandemic in developing countries. It includes updates from results of earlier studies to reflect newer and more accurate data on the pandemic’s characteristics.
Section 1: Puzzling Out Progress, AVAC Report - AVAC, 2009
In the first section of the Report, "Puzzling Out Progress," we report on the AIDS vaccine field, where there's an energized focus on discovery, innovation, and basic science.
Pursuing Prevention: Are there missing pieces?
Fitting AIDS Vaccine Science into the Bigger Picture
Solving the Enterprise Equation: When is a whole greater than the sum of its parts?
Steps to Success: The Step vaccine study's scientific contributions to the field
AIDS Vaccine Handbook - AVAC, 2005
Published in 2005, the AIDS Vaccine Handbook (second edition) provides an overview of the key scientific, policy, social, ethical, and economic challenges related to AIDS vaccine development. The easy-to-read, lively essays are written by community educators and advocates, trial staff, participants, scientists, policy-makers, and journalists.
Introduction to AIDS Vaccines (flash presentation) - AVAC
Check out this online tool to learn about AIDS vaccines! This version includes audio, animated graphics, and the ability to easily navigate the presentation
Michael Palm Basic Science, Vaccines and Prevention Project (BSVP) - TAG
The BSVP Project works with HIV community members, scientists, and policy makers to enhance public understanding of the science of HIV infection, address gaps in HIV research, critique the research effort, and foster cross-disciplinary collaborations to accelerate research into understanding how HIV causes disease (HIV pathogenesis) and speed the development of effective immune-based therapies, preventive technologies, and a cure.
AIDS Vaccine Blueprint 2008: A Challenge to the Field, A Roadmap for Progress - IAVI, 2008 (précis) (full)
In its biennial AIDS Vaccine Blueprint: A Challenge to the Field, a Roadmap for Progress, IAVI puts forth a series of concrete recommendations to help guide future AIDS vaccine research and development, including a series of interim milestones against which progress in the field can be charted.
VaxLit AIDS Vaccine Literacy Toolkit - IAVI
The VaxLit Toolkit, consisting of a reference manual, a participatory training guide, fact sheets and a user guide, can be adapted for use in various cultural and linguistic contexts. The toolkit is intended for use by the HIV and AIDS field at large, not exclusively by IAVI and its affiliated research centers.
Scientific Strategic Plan - Global HIV Vaccine Enterprise
The Enterprise Scientific Strategic Plan (SSP), published in 2005, described the major challenges facing the field and made recommendations for changes necessary to accelerate HIV vaccine research at that time. Since its publication, much has changed. Importantly, the unanticipated results of the Phase IIb STEP and Phambili clinical trials were announced in 2007, serving as a wake-up call to the HIV community that the search for an HIV vaccine remains an elusive goal requiring an even greater commitment of resources, new ideas, and novel approaches.
Ending AIDS: The Search for a Vaccine (DVD) - 2005
The Ending AIDS: The Search for a Vaccine DVD is the complex and compelling story of one of the greatest scientific and technological challenges ever: the search for an AIDS vaccine.
The HIV Vaccines Awareness Raising Programme and The HIV Vaccines Community Education Programme - SAAVI
Finding Your Way: A guide to understanding ethical issues related to preventive HIV vaccine clinical trial participation - AVAC & ICASO, 2005
Developed by AVAC in partnership with the International Council of AIDS Service Organizations (ICASO), this guide provides an introduction to the ethical principles raised in preventive HIV vaccine research and development, and examples of some of the actions taken to honor those principles.
Table contains information about ongoing trials of HIV vaccine trials.
Vaccine Fact Sheet (PDF) - AVAC
This fact sheet provides basic information on AIDS vaccines, one of the options being tested now as part of the effort to identify additional tools to reduce the risk of HIV transmission. There are no vaccines as yet to prevent HIV infection.
Thai AIDS Vaccine Trial Update page - AVAC
This webpage provides materials to help our readers in anticipating and understanding the results of the Phase III AIDS vaccine trial in Thailand.
Vax update page: Step, Phambili, PAVE 100, and HVTN 505 - AVAC
This page includes information on the Step and Phambili trials of Merck's MRK-Ad5 vaccine candidate (immunizations were stopped in September 2007) as well as information on the NIH Vaccine Research Center's DNA prime/Ad5 boost vaccine strategy, initially planned to be tested in the proposed PAVE 100 vaccine trial. The strategy is now slated to be tested in a test-of-concept trial known as HVTN 505.
Estimating the Impact of an AIDS Vaccine in Developing Countries, IAVI Policy Brief - IAVI, 2009
This policy brief examines the potential impact that an AIDS vaccine could have on the pandemic in developing countries. It includes updates from results of earlier studies to reflect newer and more accurate data on the pandemic’s characteristics.
Section 1: Puzzling Out Progress, AVAC Report - AVAC, 2009
In the first section of the Report, "Puzzling Out Progress," we report on the AIDS vaccine field, where there's an energized focus on discovery, innovation, and basic science.
Pursuing Prevention: Are there missing pieces?
Fitting AIDS Vaccine Science into the Bigger Picture
Solving the Enterprise Equation: When is a whole greater than the sum of its parts?
Steps to Success: The Step vaccine study's scientific contributions to the field
AIDS Vaccine Handbook - AVAC, 2005
Published in 2005, the AIDS Vaccine Handbook (second edition) provides an overview of the key scientific, policy, social, ethical, and economic challenges related to AIDS vaccine development. The easy-to-read, lively essays are written by community educators and advocates, trial staff, participants, scientists, policy-makers, and journalists.
Introduction to AIDS Vaccines (flash presentation) - AVAC
Check out this online tool to learn about AIDS vaccines! This version includes audio, animated graphics, and the ability to easily navigate the presentation
Michael Palm Basic Science, Vaccines and Prevention Project (BSVP) - TAG
The BSVP Project works with HIV community members, scientists, and policy makers to enhance public understanding of the science of HIV infection, address gaps in HIV research, critique the research effort, and foster cross-disciplinary collaborations to accelerate research into understanding how HIV causes disease (HIV pathogenesis) and speed the development of effective immune-based therapies, preventive technologies, and a cure.
AIDS Vaccine Blueprint 2008: A Challenge to the Field, A Roadmap for Progress - IAVI, 2008 (précis) (full)
In its biennial AIDS Vaccine Blueprint: A Challenge to the Field, a Roadmap for Progress, IAVI puts forth a series of concrete recommendations to help guide future AIDS vaccine research and development, including a series of interim milestones against which progress in the field can be charted.
VaxLit AIDS Vaccine Literacy Toolkit - IAVI
The VaxLit Toolkit, consisting of a reference manual, a participatory training guide, fact sheets and a user guide, can be adapted for use in various cultural and linguistic contexts. The toolkit is intended for use by the HIV and AIDS field at large, not exclusively by IAVI and its affiliated research centers.
Scientific Strategic Plan - Global HIV Vaccine Enterprise
The Enterprise Scientific Strategic Plan (SSP), published in 2005, described the major challenges facing the field and made recommendations for changes necessary to accelerate HIV vaccine research at that time. Since its publication, much has changed. Importantly, the unanticipated results of the Phase IIb STEP and Phambili clinical trials were announced in 2007, serving as a wake-up call to the HIV community that the search for an HIV vaccine remains an elusive goal requiring an even greater commitment of resources, new ideas, and novel approaches.
Ending AIDS: The Search for a Vaccine (DVD) - 2005
The Ending AIDS: The Search for a Vaccine DVD is the complex and compelling story of one of the greatest scientific and technological challenges ever: the search for an AIDS vaccine.
The HIV Vaccines Awareness Raising Programme and The HIV Vaccines Community Education Programme - SAAVI
Finding Your Way: A guide to understanding ethical issues related to preventive HIV vaccine clinical trial participation - AVAC & ICASO, 2005
Developed by AVAC in partnership with the International Council of AIDS Service Organizations (ICASO), this guide provides an introduction to the ethical principles raised in preventive HIV vaccine research and development, and examples of some of the actions taken to honor those principles.