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PrEP Resources

Clinical trial specific PrEP resources:

PrEP Fact Sheet - (PDF) - January 2010
This fact sheet provides basic information on microbicides, one of the options being tested now as part of the effort to identify additional tools to reduce the risk of HIV transmission.

PrEP Trials Table - (PDF) (JPG) - December 2009
Table contains information about ongoing trials of oral PrEP and topical microbicides.

PrEP Trials Map - (PDF) (JPG) - December 2009
PrEP-specific map gives a view of ongoig and completed PrEP trials worldwide.

PrEP Trials Timeline - (PDF) (JPG) - December 2009
Timeline charts past PrEP trials and provides estimated end-dates for ongoing trials.

FEM-PrEP Trial Newsletter (Issue 2 - July 09), (Issue 1 - January 09)
The FEM-PrEP clinical trial is led by Family Health International (FHI) and is designed to test the safety and effectiveness of Truvada for HIV prevention.  The FEM-PrEP Trial newsletter provides news and updates on the trial progression.

iPrEx Trial Update (Q2 2009) -
A publication providing news on PrEP and the Chemoprophylaxis for HIV prevention in Men (iPrEx) study.  Features interviews with study staff and participants, profiles of the communities involved, and issues surrounding PrEP and HIV prevention overall.

Timeline -
This page provides details the expected efficacy trial results in HIV prevention research.

Preparing for PrEP resources:
PrEP Fact Sheet - AVAC, November 2009  

PrEP Primer - AVAC, November 2009  

This new resource that provides an introduction to pre-exposure prophylaxis (PrEP), including basic information on PrEP strategies being studied, the scientific rationale for PrEP, the state of the research, who is involved in PrEP, what additional research may be needed, and how to prepare for upcoming trial results.

Anticipating/Understanding results from PrEP trials (English and Spanish) - AVAC, August 2008
This report provides background on PrEP research, the status of current clinical trials, and issues concerning effective delivery should PrEP prove effective. It closes with a list of priority issues that need attention from governments, global health institutions, donors, researchers, and advocates.

A Lexicon of Intermittent PrEP Possibilities - PrEP Committee Research Working Group, February 2009
What is iPrEP? Various intermittent dosing concepts have been discussed. To learn more about what the field is considering, check out the iPrEP glossary. 

Meeting Summary for Trials of Intermittent Dosing of Pre-Exposure Prophylaxis (PrEP) - AVAC Think Tank, December 2008
In December 2008, AVAC held a one-day think tank where colleagues from multiple agencies and research disciplines discussed key scientific questions to be addressed in evaluating the merits of future prevention research on intermittent use of pre-exposure prophylaxis (“iPrEP”) for prevention of HIV.

Preparing for PrEP: Policy, Practice and Politics - AVAC Think Tank on PrEP Financing in the US, December 2008
Colleagues from multiple disciplines met for a one-day, AVAC-sponsored think tank examining how PrEP for HIV prevention might be funded or reimbursed through insurance mechanisms in the United States should it prove safe and effective. The think tank took forward discussions on PrEP implementation strategies by identifying key regulatory, legal, and financial challenges to PrEP implementation.

The PrEP Implementation Puzzle: Many missing pieces, AVAC Report 2009 - AVAC, May 2009

Part of the Solution: Setting expectations for WHO and UNAIDS, AVAC Report 2009 - AVAC, May 2009

Research Rashomon: Lessons from the Cameroon Pre-exposure Prophylaxis Trial Site - Global Campaign for Microbicides, May 2009

Preventing Prevention Trial Failures: A Case Study and Lessons for Future Trials from the 2004 Tenofovir Trial in Cambodia - Global Campaign for Microbicides, May 2009

Oral Tenofovir Controversy II. Report of the tenofovir controversy from the perspectives of the community voices from the field - New HIV Vaccine and Microbicide Advocacy Society, April 2009

"Pre-Exposure Prophylaxis: Could It Work?" - Sharon Hillier's plenary at CROI 2009, February 2009

PrEP 101 Slide set - AVAC, May 2009

PrEP: What is it? How may it help women? PowerPoint presentation - Global Campaign for Microbicides, August 2009

PrEP: What does it mean for women?  Fact sheet - Global Campaign for Microbicides, August 2009

 

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