The announcement today that immunizations in a large-scale HIV vaccine trial have been stopped early after an independent scientific review board determined that the vaccine being tested is not effective is a reminder of how challenging it is to develop an effective AIDS vaccine, AVAC said.
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The Treatment Action Group (TAG) and AVAC released their latest report, Funding Scientific Innovation: Global Investments in HIV Treatment Research and Development in 2010 and 2011.
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Results from a large-scale HIV prevention trial among African women known as VOICE (Vaginal and Oral Interventions to Control the Epidemic) provide an urgent reminder that products must meet the needs of the people using them.
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The blueprint also recognizes that ending AIDS will not be easy or quick. While current options can have a tremendous impact, continued science and innovation are essential to ultimately halt new HIV infections and deaths from AIDS.
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AVAC released "Achieving the End: One Year and Counting," offering its critical assessment of progress achieved since global leaders began to discuss the opportunity to begin to end AIDS in late 2011.
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AVAC today welcomed CDC guidelines on the use of the antiretroviral drug TDF/FTC or Truvada as pre-exposure prophylaxis (PrEP) among sexually active heterosexual men and women.
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Three clinical trials have proven that VMMC can reduce female to male transmission of HIV by approximately 60%. If scaled up to reach 80% of adolescents and adult men within five years, and coverage is thereafter maintained, VMMC has the potential to avert more than 3.4 million new HIV infections...
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Two of the world’s leading AIDS advocacy organizations today released a global action agenda aimed at accelerating progress towards the end of the AIDS epidemic. The recommended actions could accelerate achievement of a “tipping point” in the global AIDS epidemic, at which the number of...
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AVAC today hailed the decision by the US FDA to approve the antiretroviral drug TDF/FTC or Truvada for use as PrEP among sexually active HIV-negative adult men and women.
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African Advocates Launch Movement to Build Support for Voluntary Medical Male Circumcision in Key Countries and Establish www.TruthAboutVMMC.org
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Publication of data from three trials of pre-exposure prophylaxis (PrEP) for HIV provides strong evidence that HIV-negative men and women who consistently take a daily antiretroviral (ARV) pill can significantly reduce their risk of HIV infection.
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AVAC hails the recommendation by an FDA Advisory Committee that emtricitabine/tenofovir disoproxil fumarate (TDF/FTC or Truvada) be approved for use as pre-exposure prophylaxis (PrEP) among sexually active adult men and women.
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A group of 14 leading HIV/AIDS and health organizations stated their support for Food and Drug Administration (FDA) approval of TDF/FTC or Truvada as pre-exposure prophylaxis (PrEP) to prevent HIV infection in adult men and women.
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AVAC strongly supports the California HIV/AIDS Research Program (CHRP) in launching new studies to evaluate the “real-world” use of oral pre-exposure prophylaxis (PrEP).
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Gilead Sciences announced that it has submitted a dossier of research data to the FDA related to the use of the antiretroviral treatment drug TDF/FTC as a pre-exposure prophylaxis (PrEP) HIV prevention strategy.
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AVAC today issued a science-based agenda for ending the AIDS epidemic within our lifetimes. The new report, titled The End?, is a unique strategic vision encompassing key steps to accelerate impact with existing HIV prevention tools, emerging strategies and longer term research.
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The announcement today that the 1% tenofovir gel arm of a large-scale HIV prevention trial known as VOICE will stop early is disappointing but is not the end of the road for tenofovir gel or antiretroviral (ARV)-based microbicides.
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AVAC welcomes today’s remarks by U.S. Secretary of State Hillary Rodham Clinton as the first step in an ambitious vision for ending the global AIDS epidemic and calls for expanded HIV testing, full implementation of recent biomedical breakthroughs.
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We urge the FDA and Gilead Sciences to reconsider plans to combine the approval for a prevention indication for both men who have sex with men, including transgender populations (MSM) and heterosexuals into a single filing. The combination could unnecessarily delay approval for MSM, the group at...
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Thirteen prominent U.S. HIV/AIDS organizations have issued an open letter to the U.S. Food and Drug Administration and Gilead Sciences calling for prompt regulatory review of pre-exposure prophylaxis (PrEP) for HIV prevention in gay and bisexual men and transgender women (men who have sex with...
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The announcement today that one arm of a large-scale HIV prevention trial known as VOICE will stop early is disappointing, but must be seen in context, according to the global advocacy organization AVAC.
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A copy of the sign-on letter supporting an informed debate on PrEP for gay and bisexual men is below. Openly HIV-positive gay and bisexual men who wish to add their name to the letter can do so at: http://tinyurl.com/pozPrEPletter.
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The report argues that capitalizing on recent promising scientific breakthroughs will require substantial additional and sustained investment from a broader set of donors.
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Results from two African studies of pre-exposure prophylaxis, or PrEP, released today provide clear evidence that the antiretroviral drugs used to treat HIV can also be used to prevent HIV among heterosexual men and women at risk of HIV infection.
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An international coalition of scientists and activists today launched a common platform for ending the AIDS epidemic. The broad-based international coalition issued a statement calling for world leaders to support a rational, evidence-based approach to responding to AIDS.
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The sponsors of a randomized clinical trial known as HPTN 052, which is evaluating combination antiretroviral therapy for HIV prevention, announced that randomization would halt due to overwhelming evidence of benefit.
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The Independent Data Monitoring Committee for the FEM-PrEP study determined that the trial be discontinued. This is disappointing but there are reasons to be hopeful.
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A new report from the Women’s HIV Prevention Tracking Project (WHiPT), a collaborative initiative of AVAC and the ATHENA Network, features an unprecedented collection of voices from Kenya, Namibia, South Africa, Swaziland and Uganda reflecting on what male circumcision for HIV prevention means...
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“This is a great day in the fight against AIDS. The positive results of the iPrEx oral PrEP study are a major milestone in HIV prevention research and provide important information about how antiretroviral drugs might be used for prevention by HIV-negative people at high risk for HIV...
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AVAC welcomes the new Global HIV Vaccine Enterprise Scientific Strategic Plan, released today, as a critical document that the field must implement as part of ongoing efforts to improve coordination, efficiency and transparency to quickly capitalize on recent advances in AIDS vaccine research.
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New York, NY, 3 September 2010 – AVAC today issues a call to action to donors, policy-makers, researchers and advocates to ensure that critical follow-up studies to the landmark CAPRISA 004 microbicide trial receive the economic and political support needed to move forward as quickly as...
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New York, NY – Preliminary data were presented today at the International AIDS Conference by the US Centers for Disease Control and Prevention (CDC) from a safety and acceptability trial of daily use of oral tenofovir in HIV-negative gay men and other men who have sex with men (MSM) in the...
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AVAC Contact: Kay Marshall, +1-347-249-6375, kay@avac.org UNAIDS Contact: Saya Oka, +41 22 791 1697, okas@unaids.org GPP Plays Critical Role in Moving HIV Prevention Research Agenda Forward VIENNA – The draft second edition of The Good Participatory Practice (GPP) Guidelines for...
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VIENNA (21 July, 2010) – Following significant advances in vaccine and microbicide research, importantly including results presented today of 39% efficacy in the CAPRISA 004 microbicide gel trial among women in South Africa, a new report released today warns that flat funding for HIV prevention...
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“This is a historic day for HIV prevention research. The CAPRISA 004 results are the first clinical evidence that a microbicide gel can help to prevent sexual transmission of HIV infection,” said AVAC Executive Director Mitchell Warren, reacting to the results of the landmark microbicide...
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A new report from AVAC surveys the state of biomedical HIV prevention research, including the first evidence of vaccine-induced protection in humans and the emergence of ARV-based prevention—and provides strategic recommendations for moving forward in a time of constrained resources and...
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New York, NY, December 14, 2009 — The Microbicides Development Programme announced earlier today that its MDP 301 effectiveness trial, which was conducted among almost 9,400 women in four African countries, found no evidence that the PRO 2000 microbicide reduces the risk of HIV infection.
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Category:Publications
New York, NY, , "Today marks an historic milestone in the search for an AIDS vaccine; we now have evidence that it is possible to reduce the risk HIV infection with a vaccine," said AVAC executive director Mitchell Warren, reacting to the results of the first AIDS vaccine trial to ever show...
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Cape Town -- A new report on investment in HIV prevention research in 2008 finds that HIV vaccine research funding levels decreased for the first time since investment trends have been tracked. This may have been influenced by shifts in scientific priorities, the declining economy and competing...
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New York, NY -- "It's an exciting time in HIV prevention research. We will see results from a number of critically important HIV prevention research trials this year, as well as see the start of new trials around the world that will yield important answers in the years to come," said Mitchell...
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The Clearinghouse on Male Circumcision for HIV Prevention , www.malecircumcision.org , was launched today. The Web site is designed to generate and share authoritative information about the role of male circumcision in HIV prevention.
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Mexico City, August 5, 2008 -- A new report released today shows that funding for biomedical HIV prevention research and development (R&D), including AIDS vaccines and microbicides, increased dramatically between 2000 and 2006 with only a modest increase in 2007. The report warns that the...
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Mexico City, Mexico, August 3, 2008 -- The AIDS Vaccine Advocacy Coalition (AVAC) today released a new report, Anticipating the Results of PrEP Trials, calling for increased action from governments, global health institutions, donors, researchers, and advocates to prepare for initial results --...
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New York, NY , The AIDS Vaccine Advocacy Coalition (AVAC) today released a new report that provides a comprehensive review of recent developments in AIDS vaccine research. AVAC Report 2008: The Search Must Continue explores the issues that have been raised in the wake of the failure of Merck's...
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Contact: Mitchell Warren, +1-914-661-1536, mitchell@avac.org Seattle, Washington, November 7, 2007, The AIDS Vaccine Advocacy Coalition (AVAC) released the following statement today from Executive Director Mitchell Warren in response to the release of new data from the STEP AIDS vaccine study...
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New York and Johannesburg -- The AIDS Vaccine Advocacy Coalition (AVAC) issued the following statement with regard to recent announcements about the Phambili AIDS vaccine trial in South Africa.
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The AIDS Vaccine Advocacy Coalition (AVAC) released the following statement from Executive Director Mitchell Warren about the announcement that vaccinations have been discontinued in the STEP Study, a test-of-concept trial of the MRK-Ad5 AIDS vaccine candidate developed by the Merck Research...
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New AVAC Report on the State of the AIDS Vaccine Field Calls for Accelerated Action in AIDS Vaccine and HIV Prevention Research
Seattle -- The AIDS Vaccine Advocacy Coalition (AVAC) announced today at the AIDS Vaccine 2007 Conference that it has received a five-year, $14 million grant from the...
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Call for new urgency, targets and leadership to accelerate research on HIV Vaccine Awareness Day
New York, NY -- On May 18, 1997, US President Bill Clinton called for a concerted effort to develop an AIDS vaccine within a decade. This year we mark the 10th anniversary of that call for action...
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New York, NY -- Mitchell Warren, Executive Director of the AIDS Vaccine Advocacy Coalition (AVAC) today issued the following statement regarding the new recommendations from the World Health Organization (WHO) and UNAIDS on male circumcision as an HIV prevention strategy.
"AVAC...
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New York, New York -- The AIDS Vaccine Advocacy Coalition (AVAC) heralds today's launchof the first African efficacy trial of an experimental HIV vaccine as a critical, strategic and historically-significant step in the search for an AIDS vaccine.
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HIV prevention advocates from three major civil society organizations today emphasized the importance of continued research into new HIV prevention options, despite the recent discontinuation of the Phase III effectiveness trials of the microbicide candidate, cellulose sulfate (CS).
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The HIV Vaccines and Microbicides Resource Tracking Working Group was established in 2004 to generate and disseminate high-quality, detailed and comparable data on annual investments in preventive HIV vaccine and microbicide research and development (R&D), and policy and advocacy activities....
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The AIDS Vaccine Advocacy Coalition (AVAC) is delighted to announce the launch of its new
AIDS Vaccine Clearinghouse, a comprehensive and interactive source of AIDS vaccine information on the Internet. The website, www.aidsvaccineclearinghouse.org, provides a gateway to information and a link to...
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NEW YORK - The AIDS Vaccine Advocacy Coalition (AVAC) today released a report on issues surrounding clinical testing of the antiretroviral drug tenofovir as pre-exposure prophylaxis (PREP) - a possible once-a-day pill for prevention of HIV.
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Recently clinical trials have been launched in Africa, Asia and the United States to explore the potential use of oral Tenofovir as a "once a day" pill to prevent HIV in uninfected individuals - an intervention known as pre-exposure prophylaxis (PREP). Yet concerns from a few activists opposed to...
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LOS ANGELES and NEW YORK, February 7, 2005 -- In recognition of National Black HIV/AIDS Awareness Day, the AIDS Vaccine Advocacy Coalition (AVAC) and the Black AIDS Institute (the Institute) are pleased to announce the release of Myths About HIV Vaccines and Vaccine Research, a fact sheet that...
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NEW YORK -- The AIDS Vaccine Advocacy Coalition (AVAC) praised a new partnership between the Nelson Mandela Foundation and the South African AIDS Vaccine Initiative (SAAVI), which was announced today in Johannesburg.
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NEW YORK -- The AIDS Vaccine Advocacy Coalition (AVAC) today hailed new federal legislation that provides financial incentives for private industry to develop vaccines and other antidotes to protect people in the event of biological or chemical weapon attacks.
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NEW YORK - The AIDS Vaccine Advocacy Coalition (AVAC) today expressed disappointment that the second Phase III trial of an AIDS vaccine did not show efficacy of the candidate vaccine, AIDSVAX. The trial tested AIDSVAX among 2,546 injection drug users in Thailand. "We are disappointed that...
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NEW YORK - The AIDS Vaccine Advocacy Coalition (AVAC) today released a guide for the public on the forthcoming results of the world's first AIDS vaccine efficacy trial. Results of the clinical trial of AIDSVAX, made by the biopharmaceutical company VaxGen, are expected to be released early in 2003.
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NEW YORK - The AIDS Vaccine Advocacy Coalition (AVAC) yesterday applauded South Africa's Medicines Control Council for giving the go-ahead to a long-awaited Phase I clinical trial of the countrys first AIDS vaccine.
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Advocacy Group Calls on Congress to Apply Bioterror Incentives in Battle Against Global Infectious Disease
NEW YORK - Private industry is stepping up its quest for an AIDS vaccine, but it needs increased government support to maintain the momentum, according to findings of a new survey released...
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NEW YORK - The AIDS Vaccine Advocacy Coalition (AVAC) today said it is encouraged by the announcement that Merck & Co. would team up with Aventis Pasteur to work on a potential AIDS vaccine.
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NEW YORK - The AIDS Vaccine Advocacy Coalition (AVAC) today expressed disappointment that the first efficacy trial of an AIDS vaccine failed to show protection in the study population. The trial was of the vaccine candidate AIDSVAX that is made by VaxGen.
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NEW YORK - The AIDS Vaccine Advocacy Coalition (AVAC) today announced the appointment of Huntly Collins as its first Director of Science Communication and Advocacy. Ms. Collins was a respected staff writer at The Philadelphia Inquirer from 1983 to 2001, where she covered public health and AIDS...
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AVAC Announces Appointment of New Director of Education and Outreach
NEW YORK - The Ford Foundation today announced a $250,000 grant over two years to the AIDS Vaccine Advocacy Coalition (AVAC). Founded in 1995, AVAC is a community and consumer-based advocacy organization working to accelerate...
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NEW YORK - Today, the AIDS Vaccine Advocacy Coalition (AVAC) issued its fifth independent assessment of AIDS vaccine development from a community perspective. Entitled "Five Years & Counting; Science, Urgency and Courage," the report finds that the campaign to identify an effective AIDS vaccine...
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NEW YORK - The AIDS Vaccine Advocacy Coalition (AVAC) today responded to an announcement by the National Institutes of Health (NIH) that it would not be able to run a clinical trial of immune responses with the canarypox HIV vaccine candidate. "We are very disappointed that immunology results do...
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Washington, D.C. - The Bill & Melinda Gates Foundation today announced a grant of $600,000 over three years to the AIDS Vaccine Advocacy Coalition (AVAC). Founded in 1995, AVAC is a consumer-based advocacy organization working to speed development and delivery of AIDS vaccines to populations...
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