Treatment activists from ACT UP New York founded AVAC in 1995 to speed up the development of HIV vaccines. Today, AVAC also has its sights set on biomedical HIV prevention (like microbicides , PrEP and treatment as prevention), treatment for genital herpes (HSV-2) and the protective powers of male circumcision and cervical barriers. CEO Mitchell Warren is an outspoken advocate who writes regularly in the Huffington Post about the power of prevention. He was one of the first out of the gate this year to publicy tout the “we can end AIDS” beat.