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Integrated Systems Approach Defines the Antiviral Pathways Conferring Protection by the RV144 HIV Vaccine

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Published Research

Our study highlights the important contributions of unbiased system biology approaches in defining mechanisms underlying vaccine-mediated protection. Similar approaches could lead to the identification of host-related markers associated with vaccine-conferred protection by investigating prevaccination gene-expression profiling of participants receiving the RV144 vaccine.

February 20, 2019
Nature Communications