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The Replication-Competent HIV-1 Latent Reservoir Is Primarily Established Near the Time of Therapy Initiation

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Published Research

These results suggest that the majority of the latent reservoir is seeded in response to therapy and likely is not continually formed prior to ART. HIV treatment and cure efforts could potentially exploit this information to limit the size of the reservoir when treatment is initiated.

October 9, 2019
Science Translational Medicine