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June 7, 2019
The ECHO trial (Evidence for Contraceptive options in HIV Outcomes) looked at three highly effective contraceptive methods to determine if one carried a higher risk of acquiring HIV compared to the others. Mixed data from previous observational studies had raised questions about one particularly popular method, known as DMPA-IM. The results of ECHO are due out in the coming weeks, with stakeholders from both the HIV and sexual and reproductive health fields watching closely.
In this episode of Px Pulse, AVAC spoke with two leaders from the ECHO trial team, Dr. Jared Baeten and Dr. Helen Rees, to understand what the trial can and cannot tell us. And you’ll hear leading women’s advocates from several countries where the ECHO trial took place share their demands. Carry what you learn forward as the ECHO trial raises the volume on an urgent conversation — how to empower African women around their sexual and reproductive health.
Listen to the full podcast (23:40).
Highlights
- Helen Rees lays out a public health conundrum and how the ECHO study addresses it (4:25)
- Jared Baeten and Helen Rees on how the trial was ethically designed for rigorous result (3:26)
- Jared Baeten and Helen Rees explain what can and cannot be learned from the ECHO trial (5:18)
- African women's advocates talk about why the ECHO trial is a call to action (11:22)
Additional Resources
Background on the ECHO study
- Hormonal Contraceptive and HIV Risk — AVAC-hosted webinar
- ECHO Study Background and Messages — The ECHO Consortium
- Consolidated ECHO Webinars, Factsheets and Background Documents — FP2020
- The Latest ECHO Study Information and Updates to the Medical Eligibility Criteria — WHO
- Results 4 Informed Choice Tool for Executing a Coordinated ECHO Response — The Johns Hopkins Center for Communication Programs
- 2018 Civil Society Community Dialogues — AVAC
Background on HC use and HIV
- Hormonal Contraceptives and HIV: The basics and the latest research — AVAC
- An Intro to Hormonal Contraceptives and HIV — AVAC
- Depo-Provera (DMPA) and the WHO Grading System for Contraceptives — AVAC
- WHO Guidelines for Contraceptive Methods for Women at High Risk of HIV or Living with HIV — WHO