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Trial Name Prevention Option Phase Start Date Sponsors Countries Population Candidate(s) Status
Be PrEPared - The Antwerp PrEP Project PrEP Demo Project September 2015 ITM, TBM, IWT Belgium MSM TDF/FTC (Truvada) Ongoing
Partners PrEP OLE PrEP Open Label July 2011 Bill & Melinda Gates Foundation; NIH; USAID Kenya, Uganda TDF/FTC (Truvada) Completed
Gender-Specific Combination HIV Prevention for Youth in High Burden Settings (MP3-Youth) PrEP Demo Project November 2014 New York University Kenya, United States of America Women, Men TDF/FTC (Truvada) Completed
Comprehensive HIV Prevention Package for MSM in Southern Africa: Pilot Study (Sibanye Health Project) PrEP Open Label February 2015 Emory University South Africa Men, MSM TDF/FTC (Truvada) Ongoing
AMPrEP (Amsterdam PrEP) PrEP Demo Project June 2015 Academic Medical Center, PHSA Netherlands Men, MSM Ongoing
PrEPception: Expanding Assisted Reproductive Options for Serodiscordant Couples PrEP Open Label July 2014 United States of America Women, Men Ongoing
HPTN 077 PrEP II February 2015 National Institute of Allergy and Infectious Diseases (NIAID) United States of America, Brazil, Malawi, South Africa Women, Men Cabotegravir (GSK 744) Completed
HPTN 076 PrEP II October 2014 PATH, Bill and Melinda Gates Foundation, NIAID, NIH United States of America, South Africa, Zimbabwe Women TMC 278 Completed
CDC 494 PrEP Open Label Botswana Ministry of Health, CDC, Gilead Botswana Women, Men Completed
Sisters Antiretroviral therapy Programme for Prevention of HIV –an Integrated Response (SAPPH-Ire) PrEP Demo Project July 2014 Centre for Sexual Health and HIV/AIDS Research Zimbabwe; University College London; London School of Hygiene and Tropical Medicine ; RTI; DFID; UNFPA Zimbabwe Women TDF/FTC (Truvada) Ongoing
LAC PATH PrEP Demo Project PrEP Demo Project California HIV/AIDS Research Program of the University of California; LA County HIV & STD Program; Los Angeles Gay and Lesbian Center; OASIS Clinic; AIDS Project LA; UCLA United States of America MSM TDF/FTC (Truvada) Completed
The Demo Project PrEP Demo Project October 2014 National Institute of Allergy and Infectious Diseases of the NIH United States of America MSM TDF/FTC (Truvada) Completed
PrEPBrasil PrEP Open Label October 2014 University of Sao Paulo; Centro de Referência e Treinamento DST AIDS; Oswaldo Cruz Foundation Brazil MSM TDF/FTC (Truvada) Ongoing
Wits Reproductive Health and HIV Institute PrEP Demo Project November 2014 World Health Organization, UNAIDS, O'Neil Institute of Georgetown University, London School of Hygiene and Tropical Medicine, Imperial College London; South Africa Women, HIV positive TDF/FTC (Truvada) Planned
PRELUDE Study PrEP Demo Project September 2014 Kirby Institute; AIDS Council of New South Wales (ACON) and Positive Life New South Wales Australia Women, Men TDF/FTC (Truvada) Ongoing
VicPrEP Demonstration Project PrEP Demo Project July 2014 Victorian Government Australia Women, Men, MSM TDF/FTC (Truvada) Ongoing
Benin Demonstration Project PrEP Demo Project October 2014 CHU de Quebec Benin Women TDF/FTC (Truvada) Ongoing
Partners PrEP PrEP III May 2008 Bill and Melinda Gates Foundation, University of Washington Kenya, Uganda Women, Men TDF, TDF/FTC (Truvada) Completed
CDC 4323 PrEP II February 2005 AIDS Research Consortium of Atlanta, Fenway Health, San Francisco Department of Public Health, US CDC United States of America MSM TDF Completed
CDC 4370 (Bangkok Tenofovir Study) PrEP III, II June 2005 Bangkok Metropolitan Administration Medical College and Vajira Hospital, Thailand Ministry of Health, US CDC Thailand Injecting drug users TDF Completed

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