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Oral tenofovir-based PrEP works. Faster, smarter rollout must be a top priority.

Recent clinical trials have shown clearly that daily, oral pre-exposure prophylaxis (PrEP) using the antiretroviral drugs tenofovir and emtricitabine dramatically reduces the risk of HIV infection for men and women who take it as directed. While PrEP won’t be right for every individual at risk for HIV, untold numbers of men and women will benefit—if they can access this potentially life-saving option.

So far, PrEP’s implementation has been piecemeal and incomplete. TDF/FTC is approved for use as oral PrEP in a handful of countries but, for maximum impact, PrEP rollout needs a coherent, global strategy involving many real-world demonstration projects, other research and guidance from global health agencies. At the same time, research into new PrEP formulations—such as intermittent use of pills or quarterly injections—could help improve adherence and achieve PrEP’s full potential.

What We're Reading

Rolling out PrEP right. aidsmap reporter Roger Pebody recently published a careful look at how one New York City clinic brought PrEP to a transgender community. Pebody’s story documents the steps taken by the Callen-Lourde Community Health Center to navigate the fault lines of a marginalized people and deliver a potent tool for HIV prevention.

September 19, 2016

More data show PrEP’s protective powers in couples with on HIV+ member. This study out of the University of Washington, sometimes known as the Partners PrEP Demonstration Project, followed more than 1,000 heterosexual couples in Uganda and Kenya and showed high rates of protection for the HIV-negative members of the couple. The authors say integrating ART with PrEP to African populations at high risk of acquiring HIV can result in “almost complete protection from HIV-1 transmission.”

August 23, 2016
Science Daily
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