P-Values

Discover perspectives on the latest findings, biggest challenges and most exciting successes in our collective work.

At P-Values, you’ll find updates, perspective, insights and information from staff and partners working on the frontlines of research, advocacy and implementation. P-value is a statistical term for the probability that a trial result is reliable and not the outcome of chance. 

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Global Health Watch: Pandemic Treaty Tensions, Public Health Emergency, CDC Instability & Global Fund’s Role in Bilateral Health Deals

Pandemic treaty negotiations ahead of the World Health Assembly show rising tensions, as countries push for equity in pathogen sharing, alongside the expansion of US bilateral health deals and the evolving role of the Global Fund within this shifting architecture. This issue also covers calls to declare recent US global health policy shifts a Public Health Emergency of International Concern, deepening instability at the US CDC, and updates on US government bilateral agreements.

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Global Health Watch: Pandemic Treaty Tensions, Public Health Emergency, CDC Instability & Global Fund’s Role in Bilateral Health Deals

Pandemic treaty negotiations ahead of the World Health Assembly show rising tensions, as countries push for equity in pathogen sharing, alongside the expansion of US bilateral health deals and the evolving role of the Global Fund within this shifting architecture. This issue also covers calls to declare recent US global health policy shifts a Public Health Emergency of International Concern, deepening instability at the US CDC, and updates on US government bilateral agreements.

March 2026

The Impact Report

The Impact Report highlights the power of advocacy, research translation, and partnership to advance HIV prevention and global health equity. In this first edition — the introduction of LEN in Zambia, how AVAC and partners are standing up for science, and new efforts to translate evidence for decision making.

March 2026

Bridging the Gap Between Science and Communities

In a moment when access to clear, credible HIV science has never been more urgent, AVAC is bridging the gap between global research conferences and the communities who need that information most—through real-time webinars, digestible recaps, and resources trusted by leading researchers.

March 2026

Standing Up for Science

As the US administration threatens to dismantle decades of biomedical research progress, AVAC and partners have mounted a powerful defense—highlighted by the 24-Hour Marathon to Save AIDS Research, which united 75 presenters and reached more than 7,000 people across 28 countries.

March 2026

Strengthening Access Planning

Zambia made history on World AIDS Day 2025 by becoming one of the first African countries to launch lenacapavir—just 18 months after pivotal trial results were announced. This milestone reflects years of coordinated advocacy, community engagement, and technical support that’s setting a new standard for speed and equity in HIV prevention rollouts globally.

March 2026

AVAC Roundup: Must-See Resources from the Last Week 

From spotlighting the impact of US-supported HIV research to advancing the future of the HIV response; accelerating pediatric HIV cure research to shaping the global STI agenda, AVAC is driving and tracking the critical conversations defining HIV prevention and advocacy. Read on for this week’s resources and perspectives.

March 2026

Global Health Watch: Court Blocks ACIP Overhaul, NIH Director Promises to Disburse Funds, State Dept Pulls “America First” Health MoUs

A US federal court blocked the US Administration’s efforts to overhaul the CDC’s Advisory Committee on Immunization Practices, while the NIH Director sought to reassure lawmakers over funding delays and shifting research priorities. Meanwhile, the State Department quietly removed five “America First” health agreements from public access as scrutiny grows, and Argentina announced its intent to withdraw from the WHO.

March 2026

The Benefits To Americans Of US-Supported International HIV Research

A new Health Affairs piece by Judith Auerbach, Jirair Ratevosian, and AVAC’s Mitchell Warren makes the case that cuts to US-supported global HIV research don’t just hurt partner countries. They undermine the scientific pipeline that delivers those advances to Americans most in need. As the Trump administration scales back global health investments, the US risks squandering decades of research returns just as they’re beginning to pay off.

March 2026

Global Health Watch: France Cuts Global Fund, US Bilateral Health Platform, PEPFAR Timeline Uncertainty, New Lancet Africa Journal

This week, France sharply cut its contribution to the Global Fund, adding to the replenishment shortfall. Meanwhile, the US launched a new global health funding platform tied to bilateral agreements, even as delays in MoUs and shifting timelines continue uncertainty about service delivery. And the inaugural issue of The Lancet Regional Health – Africa launched to elevate African leadership in health research and policy.

March 2026

AVAC Roundup

The last few weeks have been action-packed for HIV prevention (and for AVAC and partners), with unpacking data and discussions from CROI; injectable lenacapavir for PrEP (LEN) rolling out in a number of Eastern and Southern Africa countries; signings (and not) of “America First” Bilateral Health Agreements; and our latest quarterly STI and HIV updates. AVAC is tracking it all; see below for the key updates.

March 2026

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P-Values Blog

Discover perspectives on the latest findings, biggest challenges and most exciting successes in our collective work.

Advocates Network

AVAC’s email list for organization and individuals interested in timely updates and critical perspectives on developments in biomedical HIV prevention.

Weekly News Digest

A comprehensive round-up of HIV prevention media coverage and scientific publications.

PxPulse

Each month this podcast uses interviews, discussion and first-person reflections to explore vital topics confronting the field of HIV prevention research.

PxWire

PxWire is AVAC’s quarterly update on biomedical HIV prevention. Each issue highlights key developments, challenges and opportunities, and features a centerspread infographic that provides a visual tool for framing these issues.

Pandemic Watch

Pandemic Watch is a curated news digest on the latest pandemic prevention, preparedness, and response (PPPR) news and resources.

Press Releases

A collection of official statements from AVAC.

AVAC in the News

Media clippings featuring AVAC, its staff and close partners in the news media.