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11 September 2015 VOLUME 16 ISSUE 37

Media Coverage

  • The Institute for Tropical Medicine (ITM) in Antwerp is has launched the Be-PrEP-ared study, the first Flemish research project on the applicability of preventative HIV medication. The researchers hope that the study, which focuses on gay men, can help to reduce the high number of new HIV infections among the target group.

    September 11, 2015
    Flanders Today
  • The investigators behind the PROUD study, which found Truvada (tenofovir/emtricitabine) as pre-exposure prophylaxis (PrEP) reduced the risk of HIV infection by 86 percent among a group of high-risk men who have sex with men (MSM) in England, have published a paper outlining the finer details of the study in The Lancet.

    September 10, 2015
    aidsmeds
  • The federal government is to commence study on HIV treatments, known as Pre-exposure Prophylaxis (PrEP) and TasP (Treatment as Prevention) because of their immense positive effects on the HIV/AIDS epidemic in the country....This study is....being carried out in Nigeria to see whether it will work in real life situations among the Nigerian population under normal conditions.

    September 10, 2015
    Leadership Nigeria
  • MTV Shuga Season 4, an award winning television series from the MTV Staying Alive Foundation and MTV Base will have its world premiere on 10 September [in] Lagos, Nigeria. The sizzling sex and relationships drama and multimedia campaign developed by the MTV Staying Alive Foundation and MTV Base in partnership with NACA, PEPFAR, Bill & Melinda Gates Foundation, UNICEF and UNFPA carries important public health messaging aimed at a young audience.

    September 8, 2015
    PM News
  • Voluntary medical male circumcision is transiting into the second phase...in the number of boys and men who underwent the ‘cut’ between 2008 and 2013....At the end of the first phase, over 800,000 boys and men were circumcised in the country, and Nyanza recorded an increase from 48.2 per cent to 66 per cent. Over 3,000 service providers...were trained [and]...575 integrated outreach service provision facilities renovated and upgraded.

    September 7, 2015
    Standard Digital News
  • [From N+1 Magazine] Emily Bass on how the complex history of HIV activism jeopardises the inclusion of HIV into mainstream black and gay activism. "We need to understand and address the epidemic of amnesia that’s taken place alongside the viral rampage of HIV. The victories the AIDS-activist movement has secured have always come at a time and at a price that has made them difficult to celebrate."

    September 7, 2015
    N+1 Magazine
  • [E]ven more have interacted with someone who said he was HIV-positive but had an undetectable viral load. Many of these potential partners were looking for sex without a condom, according to survey results reported in...the Journal of Acquired Immune Deficiency Syndromes....The results suggest that discussion of PrEP use and having an undetectable viral load is becoming more mainstream among American gay men....Discussing these facts in face-to-face environments may be more challenging.

    September 7, 2015
    aidsmap
  • Jean-Claude Muhire and Ally Pacifique Mudaheranwa share two things in common: Both are aspiring storytellers and both are in a celebratory mood. The reason? The duo was recently selected among the 20 international winners in the 2015 Global Dialogues contest....The contest invites young people of less than 25 years from across the globe to come up with an original idea for a short film about HIV/AIDS, sexuality, violence against women, or alcohol, drugs and sex.

    September 6, 2015
    New Times
  • Lorrie Goss needed a moment....Goss, who is HIV-positive, was struggling with her emotions over the news that Dr. Trevor Hawkins, a leading AIDS physician, is leaving the Southwest CARE Center this month...[to] become senior medical director for medical affairs at Gilead Sciences Inc., in San Francisco, where he will be working on PrEP and the use of antiretroviral therapy, in combination with safer sexual practices, to reduce the risk of HIV infection.

    September 5, 2015
    Styrk
  • Immediate transition from post-exposure prophylaxis to pre-exposure prophylaxis and early treatment may prevent onset of HIV infection and support patient adherence, according to evidence published in Open Forum Infectious Diseases. Robert Grant,...Gladstone Institutes in San Francisco, and Dawn Smith, CDC division of HIV/AIDS Prevention, identified best practices for integrating HIV prevention strategies, based on clinical evidence and guidelines to reduce common barriers associated with HIV management.

    September 4, 2015
    Healio
  • Men incorporated knowledge of their own undetectable status into their identities as HIV-positive gay men and their sexual decision making, according to a study published in the August AIDS Education and Prevention. Being undetectable helped many men feel ‘responsible’ and ‘normal’. The findings come from in-depth, qualitative interviews with 25 gay men diagnosed with HIV in British Columbia, Canada, between 2009 and 2012.

    September 4, 2015
    aidsmap
  • Quest Diagnostics announced today that the FDA has given the company clearance to add a genital swab claim to its molecular test for herpes simplex virus types 1 and 2. The test uses real-time PCR technology to detect DNA or RNA of viruses, bacteria and other substances. It uses a proprietary process that eliminates nucleic acid extraction, and results are delivered in approximately 1 hour.

    September 3, 2015
    Healio
  • Secretary of State John Kerry during a diplomatic reception at the State Department reiterated the Obama administration’s call for a so-called AIDS free generation. “That’s our dream,” he said. “That’s what we’ve been working towards. And unlike some dreams people grow up with or take on in the course of public life, which really just get dashed against the bureaucratic resistance or the indifference of people in various places, this is one where we have really been able to make a difference.”

    September 3, 2015
    Washington Blade
  • The accidental disclosure of the names and addresses of 780 people by the 56 Dean Street clinic in London shows data breach lessons of the past are not being learned, say security advisors....Health secretary Jeremy Hunt said the breach was “completely unacceptable” and has ordered an inquiry into how the NHS handles confidential medical information, reports the Guardian.

    September 3, 2015
    Computer Weekly
  • Gilead is a prime example of an explosive growth biotech, one of several which have been offsetting big layoffs at giants like Amgen and GlaxoSmithKline. The company's fortunes were built around its blockbuster suite of HIV drugs, but the approval of its new drugs for hepatitis C--which have revolutionized the way hep C is cured--has added much, much more to the bottom line.

    September 3, 2015
    FierceBiotech
  • Two studies from the Netherlands show that while the proportion of people with HIV who are diagnosed has improved in recent years, the Netherlands lags behind some other western European countries....Diagnosis rates in 2012 were high in gay men and other men who have sex with men and non-migrant heterosexuals who attended sexual health clinics, [but]...considerably lower among MSM who did not visit sexual health clinics [and] African migrants....The lowest rates of diagnosis were in female sex workers.

    September 2, 2015
    aidsmaps
  • HIV-associated [opportunistic infections] characteristic of earlier periods in the HIV epidemic have become uncommon in HIV-infected youth,” Gayatri Mirani, Tulane University School of Medicine, and colleagues wrote. “Nevertheless, [a]dditional morbidities, including metabolic abnormalities, sexually transmitted infections, and psychiatric and neurodevelopmental disorders are becoming more common and may reflect aging, chronic HIV infection, ART-related toxicities, and chronic inflammation.

    August 24, 2015
    Healio

Published Research

  • Among women of childbearing age, the majority of estimated seasonal influenza–associated deaths occurred in HIV-infected individuals. Pregnant women experienced an increased risk of death associated with seasonal and A(H1N1)pdm09 influenza infection compared with nonpregnant women.

    October 1, 2015
    Clin Infect Dis
  • Kenneth Mayer and Douglas Krakwoer discuss why, despite the demonstrated efficacy of PrEP and the approval by regulatory bodies in the United States, uptake has not been rapid.

    September 11, 2015
    Clin Infect Dis
  • The PROUD study announced that their trial would end randomization early after the finding that gay men and other MSM in the UK who received PrEP as part of combination prevention in a community health setting had significantly lower risk of HIV compared to men who were randomly assigned to a “deferred PrEP” arm.

    September 10, 2015
    Lancet
  • Kenneth Mayer and Chris Beyrer, two leading HIV prevention researcher-advocates who have helped shape the agenda for PrEP and gay men and other MSM, argue the PROUD study shows that this PrEP strategy could readily be implemented outside the controlled environment of a clinical trial, and that in the “real world” it will be sufficiently effective to warrant wider use.

    September 9, 2015
    Lancet
  • The implementation of a cohort of HIV-positive patients in care in Guatemala is feasible and has provided national HIV indicators to monitor and evaluate the HIV epidemic. The identified percentages of late presenters and high rates of LTFU will help the Ministry to target their current efforts in improving access to diagnosis and care.

    September 8, 2015
    AIDS Research and Treatment
  • India's national AIDS and tuberculosis programmes are facing fiscal shortfalls that are beginning to show impact on the ground, Dinesh C Sharma reports from New Delhi. Bureaucratic changes and budget cuts are threatening to derail two of India's key health initiatives—the National AIDS Control Programme and the Revised National Tuberculosis Control Programme. A total of 2·1 million people in India are HIV positive and about 1·2 million new cases of tuberculosis are diagnosed every year.

    September 5, 2015
    Lancet
  • We used surveillance data for new IDU-associated HIV cases between September 1996 and December 2011....There were 176 IDU-associated HIV cases in the 2 years post-policy change; our model predicted 296 IDU-associated HIV cases had the policy remained in place, yielding a difference of 120 averted HIV cases....Policy change is an effective structural intervention for HIV prevention when it facilitates the implementation of services needed by vulnerable populations.

    September 4, 2015
    AIDS and Behavior
  • Only 67% of PCPs reported being likely to prescribe HPV vaccine to 11- and 12-year-old patients. PCPs were more likely to prescribe vaccine...if they believed HPV vaccine guidelines were clear, agreed with a mandate requirement, felt comfortable discussing HPV vaccination with early adolescent girls, and had at least 25% of their patients using public assistance to pay for their clinic visits.

    September 3, 2015
    Women's Health Issues
  • We conducted a comprehensive literature review...in Australia, Canada, New Zealand and the United States—[countries] in which Indigenous peoples share important features of colonization and marginalization....The review highlights the determinants of HIV-related behaviors including domestic violence, stigma and discrimination, and injecting drug use. Many of the factors associated with HIV risk also contribute to mistrust of health services, which in turn contributes to poor HIV and health outcomes among Indigenous peoples.

    September 1, 2015
    AIDS and Behavior
  • Eighteen studies describing 19 unique interventions met our selection criteria....Results indicate that 15 interventions provided HIV/STI information, 13 provided substance abuse prevention information, and few included content tailored to specific needs of FSW. Our findings suggest that current HIV/STI prevention efforts in the US do not adequately address the needs of FSW.

    September 1, 2015
    AIDS and Behavior
  • We conducted four annual cross-sectional surveys (2009–2012) of urban residents (N = 1614) in a northeastern U.S. city where prevalence of HIV and other STIs is high. Findings indicate slow female condom (FC) uptake but also heterosexual men’s willingness to use them. Factors associated with men’s and women’s FC use included positive FC attitudes, network exposure, and peer influences and norms. These results suggest that men can be supporters of FC, and reinforce the need for targeted efforts to increase FC use in both men and women for HIV/STI prevention.

    September 1, 2015
    AIDS and Behavior
  • HIV prevalence was 11.3%, HSV-2 30.2%, active syphilis 6.9% and hepatitis B 1.2%. In the previous 12 months, 84% of MSM reported casual male sex partners and 25% sex work. Only 48% of MSM consistently used condoms with male partners and 54% had ever been tested for HIV. Of 17% of MSM reporting a female partner, consistent condom use was 6%. HIV infection was associated with age 25 or older, active syphilis and homosexual self-identification.

    September 1, 2015
    AIDS and Behavior
  • The results from two-level multinomial logistic regression models suggest that high socioeconomic composition of the student body in school decreases the odds of initiation of sexual activity, independent of other important features of schools and individual-level characteristics. This study also finds that the association between school socioeconomic composition and sexual activity is statistically significant among male adolescents but not female adolescents, suggesting that schools’ socioeconomic contexts may be more relevant to male adolescents’ initiation of sexual activity.

    September 1, 2015
    Studies in Family Planning

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