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Multipurpose Prevention Technologies

HIV prevention and women’s reproductive health go hand in hand.

HIV prevention doesn’t happen in isolation. Even when people are at high risk for HIV, avoiding infection is but one factor in a complex set of decisions about their health and well-being. For women worldwide, those decisions include childbearing and reproductive and sexual health.

Multi-purpose prevention technologies are now in development to simultaneously prevent unintended pregnancy and protect against HIV and other sexually transmitted infections. By addressing multiple health concerns in convenient, easy-to-use formulations, these technologies might also help ensure high levels of product adherence. Multiple versions are entering early clinical trials now. Many important questions about efficacy, acceptability and adherence need to be addressed as this research proceeds.

What We're Reading

All women had highest preference for injectable ARVs, with oral PrEP having high preference if injectable ARVs are not available. Adult women will use the ring, but adolescent women will not. Importantly, even with three additional prevention products, all providing pregnancy and STI protection, > 14 percent of women will remain unprotected and > 31 percent of the baseline acquisition risk will remain. Incorporating multiple prevention components into new ARV-based prevention products may increase their uptake and impact among women.

September 25, 2020
BMC Infectious Diseases

By leveraging the existing market for OCPs and assuming modest conversion from condom users and women with an unmet need for contraception, the DPP could lead to a 2- to 10-fold increase in PrEP usage in these 15 sub-Saharan African countries, expanding the broader public health benefit of this proven HIV prevention strategy.

July 31, 2020
BMJ Sexual and Reproductive Health
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