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Ethical Considerations in Biomedical HIV Prevention Trials


July 2007

The successful development of effective HIV preventive interventions requires a large international cooperative effort drawing on partners from health sectors, inter-governmental organizations, government, research institutions, industry, and affected populations. It also requires these partners to address the difficult ethical concerns that arise during the development of biomedical HIV prevention products. UNAIDS published this update to a guidance document on ethical considerations in HIV preventive vaccine research in 2007, with further refinements in 2012. This publication reflects numerous consultations and other developments related to the conduct of biomedical HIV prevention trials, including vaccine trials.