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Trial Name Prevention Option Phase Start Date Sponsors Countries Population Candidate(s) Status
MK-8591-016 PrEP II September 2019 United States of America, Malawi, South Africa, Israel Men Islatravir (MK-8591) Ongoing
CONRAD B17-144 Microbicides, Multipurpose Prevention Technologies II December 2018 Kenya Women TFV/LNG ring, TFV ring Ongoing
CONRAD A15-140 Microbicides, PrEP I April 2016 United States of America Women TFV ring, TDF/FTC (Truvada) Completed
CONRAD A15-138 Microbicides, Multipurpose Prevention Technologies I September 2017 United States of America, Dominican Republic Men Levonorgestrel, tenofovir Completed
Population Council #728 Microbicides I October 2017 United States of America Women PC-6500 Completed
Population Council #558 Microbicides, Multipurpose Prevention Technologies I May 2014 Population Council United States of America Women PC-1005 gel, HEC gel Completed
OB-002H Microbicides I October 2019 SCOPE International AG Poland MSM, Women Completed
HVTN 706/ HPX3002 Mosaico HIV Vaccine III October 2019 Janssen Vaccines & Prevention B.V. United States of America, Argentina, Italy, Mexico, Peru, Poland, Spain Men Ad26.Mos4.HIV, gp140 Ongoing
CONRAD A18-146 Microbicides, Multipurpose Prevention Technologies I December 2018 CONRAD United States of America Women Elvitegravir (EVG), F/TAF Completed
Implementation of the Pre-Exposure Prophylaxis (PrEP) to HIV in Brazilian transgender women (PrEParadas) PrEP Demo Project July 2018 Brazilian Ministry of Health Brazil Ongoing
ImQuest DuoGel Microbicides I November 2017 United States of America Men, Women IQP-0528 Completed
MTN-041/ MAMMA Microbicides, PrEP Other May 2018 NIAID (DAIDS-ES: 38161) Malawi, South Africa, Uganda, Zimbabwe Women Dapivirine Ring, TDF/FTC (Truvada) Ongoing
MTN 043 Microbicides Open Label August 2020 NIAID (DAIDS-ES: 38591 ) Malawi, South Africa, Uganda, Zimbabwe Lactating women, Women Dapivirine Ring Ongoing
MTN-044/IPM 053/ CCN019 Microbicides, Multipurpose Prevention Technologies Open Label, I July 2018 United States of America Women Dapivirine-Levonorgestrel ring Completed
HVTN 125 HIV Vaccine Ib July 2019 NIAID (DAIDS-ES: 30015) United States of America Withdrawn
HVTN 127/HPTN 087 Antibody Related Research I February 2018 DAIDS United States of America Women, Men VRC07-523LS Ongoing
PV1/PrEPVacc HIV Vaccine, PrEP IIb January 2020 Sponsor: Imperial College London. Coordinating partners: P Kaleebu, E Ruzagira (MRC/UVRI & LSHTM, Uganda); J Weber/J Fox/C Kingsley (Imperial College, UK); S McCormack (UCL, UK); K Chinyenze (IAVI-Kenya); G Pantaleo/S Ding (CHUV/EVF, Switzerland) Uganda, South Africa, United Republic of Tanzania, Mozambique Men, Women DNA , MVA, Protein Ongoing
DREAM-01 Microbicides, Multipurpose Prevention Technologies I October 2016 NIAID (DAIDS-ES: 12067) United States of America, Malawi Men Ongoing
CONRAD 137 PrEP I October 2016 Women F/TAF, TDF/FTC (Truvada) Completed
HVTN 124/ PDPHV-201401 HIV Vaccine I March 2018 NIAID (DAIDS-ES: 38302) United States of America Men, Women gp120 (A,B,C,A/E)/GLA-SE, env (A,B,C,A/E)/gag (C)/GLA-SE Ongoing

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