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Trial Name Prevention Option Phase Start Date Sponsors Countries Population Candidate(s) Status
MTN-039 Microbicides, Multipurpose Prevention Technologies Open Label, I November 2019 MTN United States of America Men, Women Elvitegravir (EVG) Ongoing
Safety and Pharmacokinetic Study of HIV Prophylaxis Using Antiretroviral Intravaginal Rings in Healthy Women Microbicides Open Label June 2015 Auritec Pharmaceuticals United States of America TDF, TDF/FTC (Truvada), Maraviroc Completed
Safety and Pharmacokinetics (PK) of a Polyurethane Tenofovir Disoproxil Fumarate (TDF) Vaginal Ring (TDF IVR-002) Microbicides I January 2017 Albert Einstein College of Medicine of Yeshiva University United States of America, Kenya Women TDF Stopped Early
The Quatro Study Microbicides Open Label November 2015 CONRAD South Africa, Zimbabwe Women Completed
Safety and Pharmacokinetic Study of Oral Maraviroc and Maraviroc 1% Gel in HIV-1 Seronegative Adults (CHARM-03) Microbicides I January 2015 IPM, NIAID, NIH United States of America Women, Men Maraviroc Completed
CONRAD 128 Microbicides, Multipurpose Prevention Technologies I October 2014 CONRAD Dominican Republic, United States of America Women tenofovir, Levonorgestrel Completed
Film Antiretroviral Microbicide Evaluation (FAME-02) Microbicides I United States of America Women dapivirine gel Completed
Comparison of Tenofovir Vaginal Gel and Film Formulations (FAME-05) Microbicides Open Label November 2014 CONRAD Women 1% tenofovir gel, tenofovir Completed
A Phase I Trial to Assess the Safety of Tenofovir Gel and Film Formulations: FAME 04 Microbicides, Multipurpose Prevention Technologies I November 2013 CONRAD United States of America Women 1% tenofovir gel, HEC gel, tenofovir Completed
Pre-exposure prevention of viral entry (PREVENT) Microbicides Pre-clinical January 2014 NIH, NIAID United States of America GRFT
IPM 020 Microbicides II, I June 2009 IPM United States of America Women dapivirine gel Completed
IPM 014B Microbicides II, I July 2009 South Africa Women dapivirine gel Completed
IPM 014A Microbicides II, I September 2009 IPM Malawi, Rwanda, South Africa, Kenya Women dapivirine gel Completed
IPM 036 Microbicides I September 2015 IPM Belgium Women Dapivirine Ring Completed
IPM 035 Microbicides I Belgium Women Dapivirine Ring Completed
IPM 028 Microbicides I February 2016 IPM Belgium Women Dapivirine Ring Completed
MTN 032 Microbicides Open Label June 2016 MTN, NICHD, NIAID, NIMH, HIH South Africa, Malawi, Uganda, Zimbabwe Women, Men Ongoing
MTN 031/IPM 043 Microbicides II NIAID, NICHD, NIMH, NIH South Africa, Malawi Women Dapivirine Ring Withdrawn
MTN-037 Microbicides, Multipurpose Prevention Technologies I June 2018 DAIDS United States of America Men, Women PC-1005 gel Ongoing
MTN-036/IPM 047 Microbicides I September 2017 NIAID, NICHD, NIMH, NIH, IPM United States of America Women Dapivirine Ring Ongoing

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