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HVTN 111

Status
Ongoing
Phase
I
Objective

The study tests 2 experimental HIV vaccines in different combinations, to see if these combinations result in different immune responses in the body. (The immune system helps a person fight infections). It also tests an injection device without needles that uses pressurized air to inject the vaccine, to see if this can improve the immune responses.

 

*Trial is in follow-up*

Prevention Option(s)
HIV Vaccine
Study Design
Randomized
Double-blind
Arms and Assigned Interventions
Products
gp120
ARMs
Experimental
Clade
C
Trial Sponsors
HIV Vaccine Trials Network, DAIDS, BMGF, GSK, IPPOX
May 2016
July 2018
Enrollment
132
18
Years
40
Years
Population
Women
Men
Sites

Isipingo CRS

Westville, KwaZulu-Natal
South Africa

The Aurum Institute, Tembisa Hospital

Tembisa
South Africa

Aurum Institute

Klerksdorp
South Africa

Mbeya Med. Research Program, Mbeya Referral Hospital CRS

Mbeya
United Republic of Tanzania

Matero Reference Clinic CRS

Lusaka
Zambia