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HIV Vaccine

There is momentum and promise in the search for an HIV vaccine.

An effective preventive HIV vaccine would teach the body how to prevent HIV infection. Vaccines are the most powerful public health tools available—and an HIV vaccine would play a powerful role in ensuring the end to the AIDS epidemic.

While effective vaccines remain years away, there are more reasons for hope than ever before. Researchers are expanding on the result of a 2009 trial that showed, for the first time, that a vaccine can reduce the risk of HIV infection. They’re also pursuing groundbreaking research with other novel vaccine strategies, including broadly neutralizing antibodies that target a wide range of HIV strains. At the same time, there is also exciting work in efforts to understand if and how to cure HIV in people who are already infected. The timeline for this work is long and uncertain. Here, too, advocacy is needed to sustain momentum.

Today’s momentum depends on sustained funding. Policy makers and funders around the world must have the courage to sustain vital HIV vaccine research for years to come, and advocates must keep the pressure on them to maintain their commitments.

What We're Reading

The Lancet has published the 52-week results of APPROACH, an HIV vaccine whose 28-week results were sufficiently impressive for it to be taken forward into a human efficacy trial among 2600 young women in southern Africa. These latest results provided more details of the immune responses to the vaccine now in phase 2b efficacy trials known as Imbokodo or HVTN705.

July 13, 2018

HIV research has made two huge leaps, a groundbreaking vaccine trial and a team of researchers who have figured out how the virus hides in our bodies.

July 11, 2018

The main challenges facing the development of an HIV vaccine are scientific and are unprecedented in the history of vaccinology, including the need to protect against globally diverse virus strains and unclear immune correlates of protection. In The Lancet HIV, Linda-Gail Bekker and colleagues report an important next chapter in the quest to develop an HIV vaccine.

June 10, 2018
Lancet HIV
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