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PrEP

Oral tenofovir-based PrEP works. Faster, smarter rollout must be a top priority.

Recent clinical trials have shown clearly that daily, oral pre-exposure prophylaxis (PrEP) using the antiretroviral drugs tenofovir and emtricitabine dramatically reduces the risk of HIV infection for men and women who take it as directed. While PrEP won’t be right for every individual at risk for HIV, untold numbers of men and women will benefit—if they can access this potentially life-saving option.

So far, PrEP’s implementation has been piecemeal and incomplete. TDF/FTC is approved for use as oral PrEP in a handful of countries but, for maximum impact, PrEP rollout needs a coherent, global strategy involving many real-world demonstration projects, other research and guidance from global health agencies. At the same time, research into new PrEP formulations—such as intermittent use of pills or quarterly injections—could help improve adherence and achieve PrEP’s full potential.

What We're Reading

Pilot PrEP projects have been underway in some African countries for several years. But it has only been since late 2017 that some countries – notably Kenya and South Africa, and also eSwatini, which is the new name for Swaziland – have started serious PrEP availability programmes for wider populations.

August 6, 2018
aidsmap

A pilot project, PrEP@Home, reduced clinic visits to one a year and demonstrated that men who have sex with men in three US cities were able to carry out all necessary sampling for tests at home, finding the experience of using the PrEP@Home package acceptable, investigators report in the online edition of Clinical Infectious Diseases.

July 12, 2018
aidsmap

Public health officials are expanding efforts to get the HIV prevention pill into the hands of those at risk, in a nationwide effort to curb infections. But the officials are hitting roadblocks — the drug's price tag, which has surged in recent years, and changes in insurance coverage that put a heftier financial burden on patients.

June 30, 2018
npr

Fear of others thinking they’re promiscuous, or that they’re already infected with HIV, is a barrier to many women who might benefit from pills that help prevent the infection, a US study suggests.

June 14, 2018
Reuters
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